BiophysicsbioRxivPreprint
The role of positively charged small biomolecules in the aggregation of hyperphosphorylated tau in Alzheimer's disease
Jinmin Lee, Kyubin Lee, Min Soo Kim…·Sang Hak Lee
This study identifies electrostatic interactions between hyperphosphorylated tau and polyamines as crucial for tau aggregation in Alzheimer's disease and observes the transition from aggregates to fibrils.
DOI 10.1101/2023.10.19.563032