Molecular BiologyDisease Models & MechanismsPeer-reviewed
Comparative multi-omics analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency
Nicole M. Sayles, Jill S. Napierala, Josef Anrather…·Giovanni Manfredi
The paper compares multi-omics data from three mouse models of partial frataxin deficiency to assess mitochondrial stress in the heart, finding mild transcriptional changes despite severe FXN reduction.
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