NeurosciencebioRxivPreprint
The Alzheimer's disease risk gene BIN1 modulates neural network activity via the regulation of L-type calcium channel expression in human-induced neurons
Orthis Saha, Ana Raquel Melo de Farias, Alexandre Pelletier…·Marcos R. Costa
This study shows BIN1 regulates L-type calcium channels in neurons, affecting calcium homeostasis and electrical activity, and links these changes to Alzheimer's disease pathology.