ImmunologybioRxivPreprint
DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases
Franklin L. Zhong, Kim Robinson, Chrissie Lim…·Bruno Reversade
This study identifies DPP9 as an endogenous inhibitor of the NLRP1 inflammasome, showing its role in preventing auto-inflammatory diseases through regulation of NLRP1 activity.