Author

John Luke McConn

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:machine learning (classical)· 2 Research Focus:dimensionality reduction· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anand V. SastryiD· 2 shared Bernhard Ørn PalssoniD· 2 shared Cameron R. Lamoureux· 2 shared Daniel Craig ZielinskiiD· 1 shared Katherine DeckeriD· 1 shared Kevin RycheliD· 1 shared Saugat PoudeliD· 1 shared Ye GaoiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Anand V. SastryORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioinformaticsBMC BioinformaticsPeer-reviewedDec 1, 2021

Optimal dimensionality selection for independent component analysis of transcriptomic data

John Luke McConn, Cameron R. Lamoureux, Saugat Poudel…·Anand V. Sastry

This paper introduces OptICA, a method for selecting optimal dimensionality in ICA of transcriptomic data, showing it outperforms existing methods across multiple datasets.

62 citations

bulk RNA-seqmachine learning (classical)

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 8, 2021

A multi-scale transcriptional regulatory network knowledge base for Escherichia coli

Cameron R. Lamoureux, Katherine Decker, Anand V. Sastry…·Bernhard Ørn Palsson

The paper constructs a transcriptional regulatory network for Escherichia coli using machine learning on a large RNA-seq compendium, identifying regulatory modules and novel regulons.

17 citations

E. colibulk RNA-seq

𝕏 PostBluesky