PathologybioRxivPreprint
Hypoxia versus immune depletion - immune profiling and treatment cessation provide mechanistic insights and considerations for translation in Leigh syndrome
Elizaveta A. Olkhova, Ernst‐Bernhard Kayser, Anastasia Dimitriou…·Simon C. Johnson
This study investigates the effects of hypoxia and immune interventions in a mouse model of Leigh syndrome, showing that immune cell depletion suppresses disease and hypoxia cessation accelerates disease onset.
DOI 10.64898/2026.08.14.744649