Small molecule inhibition of the mitochondrial lipid transfer protein STARD7 attenuates influenza viral replication
Shipra Sharma, Oyahida Khatun, Jihaan Adonis…·Sumit K. Chanda
This paper identifies a small molecule, M4, that inhibits influenza A and B replication by targeting the host protein STARD7, preventing vRNP nuclear export and demonstrating synergistic antiviral effects with baloxavir in mice.