Author

Jonathan D. Zakary

Leipzig University

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Bioinformatics· 1

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Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

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Felipe EngelbergeriD· 1 shared Georg KünzeiD· 1 shared

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2023-2023 · peak 1/yr

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Felipe EngelbergerORCID

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1 paper

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BioinformaticsbioRxivPreprintFeb 27, 2023

Directing Protein Design Choices by Per-Residue Energy Breakdown Analysis with an Interactive Web Application

Felipe Engelberger, Jonathan D. Zakary, Georg Künze

The paper introduces ENDURE, a web tool for analyzing energetic contributions of protein mutations to guide design, showing it improves thermodynamic stability in PET-degrading enzymes.

DOI 10.1101/2023.02.27.530287

protein sequencestatistical model

𝕏 PostBluesky