NeuroscienceStructurePeer-reviewed
The binding of palonosetron and other antiemetic drugs to the serotonin 5-HT3 receptor
Eleftherios Zarkadas, Hong Zhang, Wensheng Cai…·Hugues Nury
The paper reports the cryo-EM structure of the palonosetron-bound 5-HT3 receptor and investigates binding modes of antiemetic drugs using molecular dynamics.
33 citations