Hugues Nury

The paper structures the honeybee GABAA RDL receptor to reveal three ligand binding sites and their associated conformations, highlighting allosteric modulation mechanisms and potential for new insecticides.

The paper uses cryo-EM and single-channel recordings to show that acetylcholine receptor subunits transition asynchronously, leading to a sequential activation mechanism.

This study investigates how vortioxetine interacts with human and rodent 5-HT3 receptors, revealing structural differences and mechanisms of action.

The paper reports the cryo-EM structure of the palonosetron-bound 5-HT3 receptor and investigates binding modes of antiemetic drugs using molecular dynamics.