Author

Joseph DeSautelle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron Edward FosteriD· 2 shared Bradley HammersoniD· 2 shared Brian D. WeitzneriD· 2 shared Howell F. MoffettiD· 2 shared Kevin G. HaworthiD· 2 shared Marc J. LajoieiD· 2 shared Robert A. LanganiD· 2 shared Rupesh H. Amin· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Aaron Edward FosterORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintSep 24, 2026

A Rationally Designed Transgene Drives CAR T Functional Persistence and Durable Regression of Solid Tumors

Rupesh H. Amin, Kevin G. Haworth, Howell F. Moffett…·Aaron Edward Foster

This paper designs a transgene that enhances CAR T cell persistence and tumor regression by integrating multiple engineered technologies in solid tumor models.

DOI 10.64898/2026.09.18.752754

mouseexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintAug 17, 2026

Protein design to broadly reprogram engineered T cell function

Scott E. Boyken, Sean Merillat, Robert A. Langan…·Marc J. Lajoie

This paper designs proteins to reprogram T cell signaling pathways, improving CAR-T and TCR-T performance in solid tumor models.

DOI 10.64898/2026.08.13.742806

humanexperimental assay

𝕏 PostBluesky