Genetic & Genomic MedicineFrontiers in PharmacologyPeer-reviewed
Near, far, wherever you are: Phenotype-related variation in pharmacogenomic effect sizes across the psychiatric drug literature.
Siobhan K. Lock, Djenifer B. Kappel, Jude Hutton…·Antonio F. Pardiñas
This study quantifies pharmacogenomic effect sizes for psychiatric drugs, finding larger effects for proximal outcomes like bioavailability than distal outcomes like efficacy and toxicity.
DOI 10.3389/fphar.2025.1719761