Developmental BiologybioRxivPreprint
A Synergistic Desmin-SPARC Axis Regulates Cardiac Stem Cell Differentiation and Promotes Cardiomyogenesis through Autocrine Regulation
Lucia M. Leitner, Martina Schultheis, Franziska Hofstetter…·Georg Weitzer
The paper shows that desmin induces SPARC secretion in cardiac stem cells, promoting cardiomyogenesis through autocrine signaling and enhancing myocardial transcription factor expression.
DOI 10.1101/2024.03.28.587296