Systems BiologyNaturePeer-reviewed
Global architecture of the nucleus in single cells by DNA seqFISH+ and multiplexed immunofluorescence
Yodai Takei, Jina Yun, Shiwei Zheng…·Long Cai
The paper maps chromatin states, DNA loci, and gene expression in single mouse embryonic stem cells using DNA seqFISH+ and immunofluorescence, revealing nuclear zones and subpopulations with distinct chromatin features.
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