Systems BiologyAnalytical ChemistryPeer-reviewed
Proteome-wide structural probing of low-abundant protein interactions by crosslinking
Julius Fürsch, Kai-Michael Kammer, Stefan G. Kreft…·Florian Stengel
This study identifies a bias in proteome-wide crosslinking towards high-abundant proteins and shows how optimizing kinetic parameters can enhance detection of lower-abundant proteins.
52 citations