Jun Lv

Multi-ancestry MHC-pQTL mapping reveals disease-linked HLA protein networks and shared genetic architecture

This study maps MHC-pQTL across ancestries, identifying genetic associations with plasma proteins and linking HLA genes to immune-related traits.

Copy number variant association analysis in 94,730 Chinese adults reveals loci influencing anthropometric and cardiometabolic traits

This study identifies 19 CNV associations with anthropometric and cardiometabolic traits in 94,730 Chinese adults, expanding ancestry diversity in CNV research.

Phenome-wide associations of polygenic scores for schizophrenia and major depression in 100,000 Chinese adults

This study examines polygenic scores for schizophrenia and major depression in Chinese adults, finding associations with various traits and highlighting ancestry-specific genetic correlations.

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and non-human primates

This study evaluates the efficacy and safety of AAV1-hOTOF gene therapy in mice and non-human primates for treating DFNB9 hearing loss.

A High-resolution Haplotype-resolved Reference Panel Constructed from the China Kadoorie Biobank Study

The paper constructs a high-resolution haplotype-resolved reference panel from the China Kadoorie Biobank study and demonstrates its superior performance in imputing microarray data compared to existing panels.

Mapping and Inheritance analysis of a novel dominant rice male sterility mutant, OsDMS-1

The paper identifies a novel dominant rice male sterility mutant, OsDMS-1, and reports three loci controlling its sterility, conflicting with classical genetic analysis.

Quantitative Relations in Protein and RNA Folding Deduced from Quantum Theory

The paper deduces quantitative relations in protein and RNA folding from quantum theory and validates them against experimental data.