Pharmacology & ToxicologybioRxivPreprint
A corticopapillary Gdf15 response links maladaptive collecting duct remodeling to polyuria during lithium exposure
Lucie Zerarga, Marie Himbert, Mélanie Try…·Nahid Tabibzadeh
This study identifies Gdf15 as a key mediator of lithium-induced collecting duct dysfunction and remodeling, linking spatial stress responses to functional and structural kidney injury.