Author

Juvid Aryaman

Primary ORCID profile (0000-0002-2605-052X · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Juvid AryamaniD2 papers · Imperial College London

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

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Iain G Johnston· 1 shared Nick S Jones· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperCell Biology

Iain G Johnston

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1 paper

Recent·Most cited

Cell BiologyBiochemical JournalPeer-reviewedNov 24, 2017

Mitochondrial DNA Density Homeostasis Accounts for the Threshold Effect in Human Mitochondrial Disease

Juvid Aryaman, Iain G Johnston, Nick S Jones

The paper develops a mathematical model to explain the threshold effect in mitochondrial disease by showing cells maintain wild-type mtDNA density through volume reduction until a minimum volume is reached, after which energy production pathways are upregulated.

DOI 10.1042/bcj20170651

humanbulk RNA-seq

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