Author

K. A. Fader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

C. J. Somps· 1 shared G. N. Cholico· 1 shared H. H. Wang· 1 shared I. D. Pardo· 1 shared M. P. Sirivelu· 1 shared N. A. Zacharewski· 1 shared R. C. Kovi· 1 shared R. Nault· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

C. J. Somps

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2 papers

Recent·Most cited

Circulating neurofilament light chain as a promising biomarker of AAV-induced dorsal root ganglia toxicity in nonclinical toxicology species

K. A. Fader, I. D. Pardo, R. C. Kovi, C. J. Somps, H. H. Wang, V. S. Vaidya, S. K. Ramaiah, M. P. Sirivelu

This study evaluates neurofilament light chain (NF-L) as a biomarker for AAV-induced dorsal root ganglia toxicity in rats and monkeys, showing strong correlation with lesion severity.

bioRxiv · Dec 23, 2021Pharmacology & Toxicology

Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation

G. N. Cholico, R. R. Fling, N. A. Zacharewski, K. A. Fader, R. Nault, T. R. Zacharewski

This study shows TCDD induces a futile cycle in hepatic fatty acid metabolism by repressing β-oxidation genes and increasing octenoyl-CoA, which inhibits ECHS1 activity.

bioRxiv · Jan 21, 2021Pharmacology & Toxicology