Author

K. Bargsten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Clery· 1 shared A. E. Prota· 1 shared A. Saha· 1 shared C.-H. Lin· 1 shared D. Lucena-Agell· 1 shared F. H. Allain· 1 shared F. Josa-Prado· 1 shared G. Palermo· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Clery

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structural basis for Cas9 off-target activity

M. Pacesa, C.-H. Lin, A. Clery, A. Saha, P. R. Arantes, K. Bargsten, M. J. Irby, F. H. Allain, G. Palermo, P. Cameron, P. D. Donohoue, M. Jinek

This study identifies structural mechanisms enabling Cas9 off-target activity through non-canonical base pairing and conformational changes.

bioRxiv · Nov 18, 2021Biochemistry

Structural insight into the stabilization of microtubules by taxanes

A. E. Prota, D. Lucena-Agell, Y. Ma, J. Estevez-Gallego, S. Li, K. Bargsten, F. Josa-Prado, J. M. Andreu, K.-H. Altmann, N. Gaillard, S. Kamimura, T. Muehlethaler, M. A. Oliva, M. O. Steinmetz, W.-S. Fang, J. F. Diaz

This study determines the crystal structures of taxane-tubulin complexes and uses simulations to elucidate how taxanes stabilize microtubules through conformational changes and ligand binding.

bioRxiv · Jul 20, 2021Biophysics