MicrobiologybioRxiv
Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive EV-A71 virulence in mice
H. K. Tee, C. W. Tan, T. Yogarajah…·Y. F. Chan
This study shows that electrostatic interactions at the five-fold axis of EV-A71 influence heparin-binding and drive virulence in mice by altering viremia and neuroinvasion.
DOI 10.1371/journal.ppat.1007863