Author

K. C. Rees

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. C. Whitehead· 2 shared A. Bergmann· 1 shared A. Jebet· 1 shared B. N. Dominy· 1 shared B. Staker· 1 shared C. Dameron· 1 shared C.-D. Pham· 1 shared E. A. Moseman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

D. C. Whitehead

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Author profile →

2 papers

Recent·Most cited

Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

J. E. Milanes, V. C. Yan, C.-D. Pham, F. L. Muller, S. Kwain, K. C. Rees, B. N. Dominy, D. C. Whitehead, S. W. Millward, M. Bolejack, J. Abendroth, I. Q. Phan, B. Staker, E. A. Moseman, X. Zhang, , J. Morris

This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.

bioRxiv · Jan 16, 2024 · PreprintBiochemistry

Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection.

A. Bergmann, K. Floyd, M. Key, C. Dameron, K. C. Rees, D. C. Whitehead, I. Hamza, Z. Dou

This study shows Toxoplasma gondii relies on its plant-like heme biosynthesis pathway for infection and demonstrates oxadiazon and its derivatives inhibit growth, suggesting heme biosynthesis as a therapeutic target.

PLOS Pathogens · May 14, 2020Peer-reviewedMicrobiology