Author

K. Chappell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Watterson· 3 shared A. A. Amarilla· 2 shared A. Isaacs· 2 shared B. Liang· 2 shared N. Modhiran· 2 shared P. Young· 2 shared A. A. Khromykh· 1 shared A. Khromykh· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

D. Watterson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 Gamma variant

C. L. Pegg, N. Modhiran, R. Parry, B. Liang, A. A. Amarilla, A. Khromykh, L. Burr, P. Young, K. Chappell, B. L. Schulz, D. Watterson

This study compares glycosylation and antigenicity of SARS-CoV-2 Wu-1 and Gamma variants, finding that an NTD mutation alters glycan site occupancy but not antibody binding.

bioRxiv · Apr 3, 2023 · PreprintBiochemistry

An alpaca-derived nanobody neutralizes the SARS-CoV-2 omicron variant

N. Modhiran, S. M. Lauer, A. A. Amarilla, P. Hewins, S. I. L. van den Broek, Y. S. Low, N. Thakur, B. Liang, G. V. Nieto, J. Jung, D. Paramitha, A. Isaacs, J. de Sng, D. Song, J. Jorgensen, , D. Watterson

This paper identifies a nanobody that effectively neutralizes the SARS-CoV-2 Omicron variants BA.1 and BA.2, showing high affinity and pre-clinical promise.

bioRxiv · Dec 27, 2022 · PreprintMicrobiology

Geographic patterns of koala retrovirus genetic diversity, endogenization and subtype distributions

M. D. Blyton, P. Young, B. D. Moore, K. Chappell

The paper analyzes KoRV genetic diversity and endogenization patterns across koala populations, revealing geographic differences in subtype distribution and endogenous sequences.

Proceedings of the National Academy of Sciences · Aug 9, 2022Peer-reviewedMicrobiology

Concerns regarding vaccination as a management strategy against koala retrovirus

B. A. Joyce, D. Watterson, A. Isaacs, K. Chappell

This paper challenges the effectiveness of a recombinant vaccine against KoRV by showing undetectable anti-Env antibodies in infected koalas, suggesting potential flaws in prior studies.

bioRxiv · May 10, 2021 · PreprintImmunology