Aberrant Transitional Alveolar Epithelial Cells Promote Pathogenic Activation of Lung Fibroblasts in Preclinical Fibrosis Modeling
E. T. Hoffman, W. R. Barboza, L. R. Rodriguez, R. Dherwani, Y. Tomer, A. Murthy, A. Bennett, A. Nottingham, A. Babu, K. Chavez, C. H. Cooper, M. C. Basil, M. S. B. Raredon, J. B. Katzen
This study identifies aberrant transitional alveolar epithelial cells in a mouse fibrosis model and shows they activate fibroblasts through a profibrotic secretome.
bioRxiv · Jun 17, 2024 · PreprintCell Biology