Author

K. Chibale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Moosa· 2 shared C. O. Omollo· 2 shared D. F. Warner· 2 shared A. Horatscheck· 1 shared A. Theron· 1 shared A. van Heerden· 1 shared A. Wasuna· 1 shared B. Bezuidenhout· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

A. Moosa

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterization of antimalarial activity of artemisinin-based hybrid drugs

D. R. M. Moreira, H. C. Quadros, L. Herrmann, J. Manaranche, L. Paloque, M. C. Borges-Silva, G. A. Dziwornu, S. D'Alessandro, K. Chibale, N. Basilico, F. Benoit-Vical, S. Tsogoeva

This study characterizes the antimalarial activity of two artemisinin-based hybrid drugs against drug-sensitive and resistant Plasmodium falciparum parasites, finding that slow peroxide bond homolysis correlates with increased efficacy against resistant strains.

bioRxiv · Jan 26, 2024Microbiology

Fusidic acid-based drug combinations exhibit enhanced activity against Mycobacterium tuberculosis

C. O. Omollo, D. F. Warner, A. Moosa, K. Chibale

This study identifies drug combinations with fusidic acid that show synergistic activity against Mycobacterium tuberculosis in vitro.

bioRxiv · Jan 19, 2023 · PreprintMicrobiology

Developing synergistic drug combinations to restore antibiotic sensitivity in drug-resistant Mycobacterium tuberculosis

C. O. Omollo, V. Singh, E. Kigondu, A. Wasuna, P. Agarwal, A. Moosa, T. R. Ioerger, V. Mizrahi, K. Chibale, D. F. Warner

bioRxiv · Dec 8, 2020Microbiology

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

J. Reader, M. E. van der Watt, D. Taylor, C. Le Manach, N. Mittal, S. Ottilie, A. Theron, P. Moyo, E. Erlank, L. Nardini, N. Venter, S. Lauterbach, B. Bezuidenhout, A. Horatscheck, A. van Heerden, , L.-M. Birkholtz

The paper screens a compound library to identify antimalarial compounds active against multiple Plasmodium life stages and transmission-blocking agents.

bioRxiv · Jun 5, 2020Microbiology