Author

K. D. LaCourse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:metagenomics· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Baryiames· 2 shared C. D. Johnston· 2 shared S. Bullman· 2 shared A. G. Kempchinsky· 1 shared C. Mengoni· 1 shared D. S. Jones· 1 shared E. McMahon· 1 shared F. E. Dewhirst· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

A. Baryiames

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fusobacterium sphaericum sp. nov., isolated from a human colon tumor, adheres to colonic epithelial cells and induces IL-8 secretion

M. A. Zepeda-Rivera, Y. Eisele, A. Baryiames, H. Wu, C. Mengoni, G. Piccinno, E. McMahon, K. D. LaCourse, D. S. Jones, H. Hauner, S. S. Minot, N. Segata, F. E. Dewhirst, C. D. Johnston, S. Bullman

The paper isolates and characterizes a novel Fusobacterium species from a human colon tumor, showing its adherence to epithelial cells and IL-8 induction.

bioRxiv · Jun 16, 2023Microbiology

The cancer chemotherapeutic 5-fluorouracil is a potent inhibitor of Fusobacterium nucleatum and its activity is modified by the intratumoral microbiota

K. D. LaCourse, A. Baryiames, A. G. Kempchinsky, C. D. Johnston, S. Bullman

This study identifies 5-fluorouracil as a potent inhibitor of Fusobacterium nucleatum in colorectal cancer and shows that intratumoral microbiota can modify its activity.

bioRxiv · Mar 12, 2022Microbiology

Coordinately regulated interbacterial antagonism defense pathways constitute a bacterial innate immune system

S.-Y. Ting, K. D. LaCourse, H. E. Ledvina, R. Zhang, M. C. Radey, H. D. Kulasekara, R. Somavanshi, S. K. Bertolli, L. A. Gallagher, J. Kim, K. M. Penewit, S. J. Salipante, L. Xu, S. B. Peterson, J. D. Mougous

This study identifies three conserved interbacterial antagonism resistance clusters in Pseudomonas aeruginosa that function independently and provide specific defense against phospholipase toxins.

bioRxiv · Aug 22, 2021Microbiology