Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection
Z. Zou, C. Obernuefemann, P. Singh, J. Pinkner, W. Xu, T. Nye, K. Dodson, F. Almqvist, S. Hultgren, M. Caparon
This study develops and tests GmPcides, dihydrothiazolo ring-fused 2-pyridone compounds, showing efficacy against Streptococcus pyogenes SSTI and biofilm formation.
bioRxiv · Jan 2, 2024 · PreprintMicrobiology