Author

K. Dunn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Dawson· 1 shared A. Hirst· 1 shared A. Ianniciello· 1 shared A. J. M. Wollman· 1 shared A. Vazquez· 1 shared D. O'Connell· 1 shared D. Sarnello· 1 shared D. Sumpton· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Dawson

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2 papers

Recent·Most cited

Mitochondrial folate metabolism inhibition drives differentiation through mTORC1 mediated purine sensing

M. M. Zarou, K. M. Rattigan, D. Sarnello, A. Dawson, A. Ianniciello, K. Dunn, M. Copland, D. Sumpton, A. Vazquez, V. Helgason

The paper shows that inhibiting mitochondrial folate metabolism drives differentiation in CML cells via mTORC1 and purine sensing, and enhances the efficacy of imatinib in reducing therapy-resistant LSCs.

bioRxiv · Dec 21, 2022 · PreprintCancer Biology

Biophysical characterization of DNA origami nanostructures reveals inaccessibility to intercalation binding sites

H. Miller, S. A. Contera, A. J. M. Wollman, A. Hirst, K. Dunn, S. Schroeter, D. O'Connell, M. C. Leake

The paper investigates intercalation binding site accessibility in DNA origami nanostructures using biophysical methods and finds that not all sites are accessible for dye intercalation.

bioRxiv · Nov 16, 2019Biophysics