A helminth mimic of TGF-β, TGM, enhances regenerative cutaneous wound healing and modulates immune cell recruitment and activation
K. E. Lothstein, F. Chen, P. Mishra, D. J. Smyth, W. Wu, A. Lemenze, Y. Kumamoto, R. M. Maizels, W. C. Gause
This study shows that TGM, a helminth-derived TGF-β mimic, accelerates wound healing and reprograms macrophage activation through TGF-β receptor interactions.
bioRxiv · Sep 24, 2022 · PreprintImmunology