Author

K. F. Santos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:biophysical modeling· 2 Approach:experimental assay· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1

Frequent Co-Authors

M. C. Wahl· 3 shared E. Absmeier· 2 shared K. Vester· 2 shared B. Kuropka· 1 shared C. Weise· 1 shared D. Burakovskiy· 1 shared M. V. Rodnina· 1 shared P. Imhof· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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3 shared papersBiochemistry

M. C. Wahl

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Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJan 28, 2021

Long-range allosteric effects - How adenine nucleotides shape the conformational landscape of the Ski2-like RNA helicase, Brr2

E. Absmeier, K. Vester, T. Ghane…·M. C. Wahl

This study investigates how adenine nucleotides influence the conformational dynamics of Brr2, revealing long-range allosteric effects between its cassettes.

DOI 10.1101/2021.01.28.428616

protein structurebiophysical modeling

𝕏 PostBluesky

BiochemistrybioRxivPreprintSep 6, 2019

Positive and negative intra-molecular modulation in a dual-cassette RNA helicase

K. Vester, K. F. Santos, B. Kuropka…·M. C. Wahl

This study shows that the inactive C-terminal cassette of Brr2 can both positively and negatively modulate the active N-terminal cassette's RNA-related activities through structural changes.

DOI 10.1101/758698

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivSep 5, 2019

Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase

E. Absmeier, K. F. Santos, M. C. Wahl

The paper presents crystal structures of Brr2 to elucidate mechanisms inhibiting intrinsic ATPase activity and how RNA binding stimulates it.

DOI 10.1016/j.str.2019.11.014

structural biologyexperimental assay

𝕏 PostBluesky