Cancer BiologybioRxiv
Regulation of eIF4F complex by the peptidyl prolyl isomerase FKBP7 in taxane-resistant prostate cancer
M. F. GARRIDO, N. J. MARTIN, C. GAUDIN…·A. CHAUCHEREAU
This study identifies FKBP7 as a molecular chaperone that regulates the eIF4F complex in taxane-resistant prostate cancer, and shows that inhibiting eIF4A can overcome resistance.
DOI 10.1158/1078-0432.ccr-18-0704