ImmunologybioRxivPreprint
Afucosylated maternal anti-dengue IgGs are a biomarker for susceptibility to dengue disease in their infants
N. K. Thulin, R. C. Brewer, R. Sherwood…·T. T. Wang
The paper identifies afucosylation of maternal anti-dengue IgGs as a biomarker for infant susceptibility to symptomatic dengue infections and explains its mechanism involving Fc{gamma}RIIIa-mediated enhancement of viral replication.
DOI 10.1101/565259