BiochemistrybioRxiv
A polymerase ribozyme increases copying fidelity through pyrophosphate-mediated RNA repair
A. D. Kent, L. L. Yang, K. H. Cole…·A. Luptak
This study shows a polymerase ribozyme can repair damaged RNA sequences through pyrophosphate-mediated mechanisms, increasing copying fidelity and enabling extended replication.
DOI 10.1073/pnas.2606892123