Cancer BiologybioRxivPreprint
PSMA-bearing extracellular vesicles secreted from prostate cancer convert the microenvironment to a tumor-supporting, pro-angiogenic state.
C. M. Machado, M. Skubal, K. Haedicke…·J. Grimm
The paper shows that PSMA-bearing extracellular vesicles from prostate cancer cells promote a pro-angiogenic tumor microenvironment by increasing VEGF-A, angiogenin, and 4EBP-1 phosphorylation.
DOI 10.1101/2022.02.25.482024