USP15 participates in HCV propagation through the regulation of viral RNA translation and lipid droplet formation
S. Kusakabe, T. Suzuki, Y. Sugiyama, S. Haga, K. Horike, M. Tokunaga, J. Hirano, Z. He, D. V. Chen, H. Ishiga, Y. Komoda, C. Ono, T. Fukuhara, M. Yamamoto, M. Ikawa, , Y. Matsuura
This study identifies USP15 as a host factor for HCV propagation, showing it regulates viral RNA translation and lipid droplet formation in hepatic cells.
bioRxiv · Oct 2, 2018Microbiology