Adipocyte JAK2 mediates aging-associated metabolic liver disease and progression to hepatocellular carcinoma
K. J. Corbit, C. G. Wilson, D. Lowe, J. L. Tran, N. B. Vera, M. Clasquin, A. N. Mattis, E. J. Weiss
This study shows that adipocyte JAK2 mediates GH-induced metabolic liver disease and progression to HCC in aged mice, highlighting adipocytes as key mediators.
bioRxiv · Jun 24, 2019 · PreprintPhysiology