Author

D. Lowe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. G. Wilson· 2 shared J. L. Tran· 2 shared A. Chang· 1 shared A. Fernandez· 1 shared A. Foster· 1 shared A. K. Bera· 1 shared A. N. Mattis· 1 shared A. Olshefsky· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

C. G. Wilson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

A. Roy, L. Shi, A. Chang, X. Dong, A. Fernandez, J. C. Kraft, J. Li, V. Q. Le, R. V. Winegar, G. M. Cherf, D. Slocum, P. D. Poulson, G. E. casper, M. L. Vallecillo-Zuniga, J. C. Valdoz, , D. Baker

This paper designs highly selective miniprotein inhibitors for integrins αvβ6 and αvβ8 with picomolar affinity and therapeutic potential in a mouse fibrosis model.

bioRxiv · Jun 12, 2023 · PreprintBiochemistry

Super-relaxed state of myosin in human skeletal muscle is fiber-type dependent

L. A. Phung, A. Foster, M. Miller, D. Lowe, D. D. Thomas

This study measures the myosin super-relaxed state (SRX) in human skeletal muscle fibers, finding fiber-type dependent differences in SRX fraction and ATP turnover.

bioRxiv · Sep 24, 2020Biophysics

Adipocyte JAK2 mediates aging-associated metabolic liver disease and progression to hepatocellular carcinoma

K. J. Corbit, C. G. Wilson, D. Lowe, J. L. Tran, N. B. Vera, M. Clasquin, A. N. Mattis, E. J. Weiss

This study shows that adipocyte JAK2 mediates GH-induced metabolic liver disease and progression to HCC in aged mice, highlighting adipocytes as key mediators.

bioRxiv · Jun 24, 2019 · PreprintPhysiology

Adipocyte Jak2 Mediates Growth Hormone-Induced Hepatic Insulin Resistance

K. Corbit, J. P. G. Camporez, J. L. Tran, C. G. Wilson, D. Lowe, S. Nordstrom, K. Ganeshan, R. J. Perry, G. Schulman, M. J. Jurczak, E. Weiss

This study shows that adipocyte Jak2 mediates GH-induced hepatic insulin resistance through an adipose-dependent mechanism.

bioRxiv · Sep 20, 2016Physiology