Author

K. Krajewski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Vaidya· 1 shared B. C. Taylor· 1 shared B. D. Strahl· 1 shared E. F. Patteson· 1 shared E. N. Weinzapfel· 1 shared F. M. Joseph· 1 shared G. C. Fox· 1 shared H. F. Taylor· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Vaidya

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A peptide derived from the SARS-CoV-2 S2-protein heptad-repeat-2 inhibits pseudoviral fusion at micromolar concentrations: Role of palmitic acid conjugation

N. Düzgünes, Z. Tao, Y. Zhang, K. Krajewski

The paper tests a palmitoylated HR2-derived peptide's ability to inhibit SARS-CoV-2 pseudoviral fusion and finds it reduces fusion activity by 76% at 10 M.

bioRxiv · May 13, 2023Microbiology

An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

K. Jain, M. R. Marunde, J. M. Burg, S. L. Gloor, F. M. Joseph, K. F. Poncha, Z. B. Gillespie, K. L. Rodriguez, I. K. Popova, N. W. Hall, A. Vaidya, S. A. Howard, H. F. Taylor, L. Mukhsinova, U. C. Onuoha, , B. D. Strahl

The paper shows that H3 tail acetylation enhances accessibility of both H3K4 methyl readers and writers, revealing an acetylation-mediated chromatin switch that modulates H3K4 methylation read-write capability.

bioRxiv · Feb 28, 2022Biochemistry

Harnessing Ionic Selectivity In Acetyltransferase Chemoproteomic Probes

Y. Jing, J. L. Montano, M. J. Levy, J. Lopez, P.-P. Kung, P. Richardson, K. Krajewski, L. Florens, M. Washburn, J. L. Meier

The paper develops a CoA-based chemoproteomic strategy to optimize probe selectivity and evaluates its application in assessing small molecule acetyltransferase inhibitors.

bioRxiv · Sep 24, 2020Biochemistry