Author

A. Vaidya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

M.-C. Keogh· 2 shared S. L. Gloor· 2 shared B. C. Taylor· 1 shared B. D. Strahl· 1 shared C. W. Hicks· 1 shared C. Wolberger· 1 shared E. F. Patteson· 1 shared E. N. Weinzapfel· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBiophysics

M.-C. Keogh

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Author profile →

4 papers

Recent·Most cited

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch

C. W. Hicks, S. Rahman, S. L. Gloor, J. K. Fields, N. L. Husby, A. Vaidya, K. E. Maier, M. Morgan, M.-C. Keogh, C. Wolberger

This study reveals that H2BK120ub blocks the nucleosome acidic patch, preventing protein binding, while H2AK119ub does not, highlighting distinct roles of these ubiquitinations in chromatin regulation.

bioRxiv · Feb 22, 2024Biophysics

An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

K. Jain, M. R. Marunde, J. M. Burg, S. L. Gloor, F. M. Joseph, K. F. Poncha, Z. B. Gillespie, K. L. Rodriguez, I. K. Popova, N. W. Hall, A. Vaidya, S. A. Howard, H. F. Taylor, L. Mukhsinova, U. C. Onuoha, , B. D. Strahl

The paper shows that H3 tail acetylation enhances accessibility of both H3K4 methyl readers and writers, revealing an acetylation-mediated chromatin switch that modulates H3K4 methylation read-write capability.

bioRxiv · Feb 28, 2022Biochemistry

Extradomain-B Fibronectin is a molecular marker of invasive breast cancer cells

Z.-R. Lu, A. Vaidya, H. Wang, V. Qian

This study identifies EDB-FN as a molecular marker of invasive breast cancer cells linked to AKT pathway activity and therapeutic response.

bioRxiv · Aug 22, 2019 · PreprintCancer Biology

A game theoretic approach to deciphering the dynamics of amyloid-β aggregation along competing pathways

P. Ghosh, P. Rana, V. Rangachari, J. Saha, E. Steen, A. Vaidya

This paper uses a game theoretic framework based on Nash equilibria to model and simulate competing pathways of amyloid-β aggregation in the presence of fatty acids, showing how rate constants control oligomer formation.

bioRxiv · Mar 18, 2019Biophysics