Cathepsin B regulates ovarian reserve quality and quantity via mitophagy by modulating IGF1R turnover.
A. Mohanty, A. Kumari, L. Kumar. S, A. Kumar, P. Birajdar, R. Beniwal, M. Athar, K. Kumar P, H. Prasada Rao
This study identifies Cathepsin B's role in regulating ovarian reserve through mitophagy and IGF1R turnover, showing its conservation in higher vertebrates.
bioRxiv · Feb 14, 2024Cell Biology