MicrobiologybioRxiv
tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector
I. Jain, M. Kolesnik, L. Minakhin…·E. Semenova
The paper shows that Cas13a cleaves tRNA anticodons to induce bacterial dormancy and activates toxin-antitoxin modules for mRNA and rRNA cleavage.
DOI 10.1126/sciadv.adl0164