Cell BiologybioRxivPreprint
sMEK1 promotes crosstalk between IRE1 and Akt signaling pathway: Evidence for a novel IRE1/sMEK1/Akt complex
O. Qadri, S. Bashir, M. Banday…·K. M. Fazili
This study identifies sMEK1 as a mediator of IRE1's negative regulation of Akt, forming a ternary complex that dephosphorylates Akt during ER stress.
DOI 10.1101/2021.07.09.451832