Author

K. M. Heidel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

A. R. Odom John· 2 shared C. S. Dowd· 2 shared C.-A. D. Burnham· 2 shared I. T. Shah· 2 shared J. J. Miller· 2 shared M. O. Mikati· 2 shared R. L. Edwards· 2 shared A. J. Jezewski· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMicrobiology

A. R. Odom John

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologyACS Infectious DiseasesPeer-reviewedOct 29, 2020

Antimicrobial prodrug activation by the staphylococcal glyoxalase GloB

M. O. Mikati, J. J. Miller, D. M. Osbourn…·A. R. Odom John

This study identifies GloB as a bacterial enzyme that activates carboxy ester prodrugs, suggesting its potential for developing targeted prodrug therapies against staphylococcal species.

DOI 10.1021/acsinfecdis.0c00582

mouseexperimental assay

𝕏 PostBluesky

MicrobiologyPLOS PathogensPeer-reviewedJun 4, 2020

Potent, specific MEPicides for treatment of zoonotic staphylococci

R. L. Edwards, I. Heueck, S. G. Lee…·A. R. Odom John

This paper identifies DXR as a druggable target for zoonotic staphylococci and develops potent prodrug inhibitors (MEPicides) that bypass transporter requirements.

DOI 10.1371/journal.ppat.1007806

mousehuman

𝕏 PostBluesky