MicrobiologybioRxiv
Cryo-OrbiSIMS for 3D molecular imaging of a bacterial biofilm in its native state
J. Zhang, J. Brown, D. Scurr…·P. Rakowska
This paper introduces Cryo-OrbiSIMS for 3D molecular imaging of bacterial biofilms, revealing the spatial distribution of quorum sensing molecules and membrane components in Pseudomonas aeruginosa.
DOI 10.1021/acs.analchem.0c01125