Cancer BiologybioRxiv
Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia.
D. Sakthivel, A. N. Brown-Suedel, F. Keane…·L. Bouchier-Hayes
This study shows caspase-2 is essential for proliferation and self-renewal of NPM1-mutated AML cells, suggesting it as a potential therapeutic target.
DOI 10.1126/sciadv.adj3145