Author

B. Le

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Ecology· 1 Evolutionary Biology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:imaging· 2 Assay:metabolomics· 2

Frequent Co-Authors

A. Diep· 2 shared A. M. Palma· 2 shared A. W. Browne· 2 shared A. Wei· 2 shared K. Nguyen· 2 shared A. F. Carisey· 1 shared A. Klos· 1 shared A. N. Brown-Suedel· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPathology

A. Diep

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia.

D. Sakthivel, A. N. Brown-Suedel, F. Keane, S. Huang, K. Mc Sherry, C. I. Charendoff, K. P. Dunne, D. J. Robichaux, B. Le, C. S. Shin, A. F. Carisey, J. M. Flanagan, L. Bouchier-Hayes

This study shows caspase-2 is essential for proliferation and self-renewal of NPM1-mutated AML cells, suggesting it as a potential therapeutic target.

bioRxiv · May 29, 2023Cancer Biology

The evolution and spread of sulfur-cycling enzymes reflect the redox state of the early Earth

K. Mateos, G. Chappell, A. Klos, B. Le, J. Boden, E. E. Stueeken, R. E. Anderson

This study uses phylogenetic analysis to show that sulfur-cycling enzyme evolution reflects changes in Earth's redox state over time.

bioRxiv · Aug 5, 2022Evolutionary Biology

Life history strategies and niches of soil bacteria emerge from interacting thermodynamic, biophysical, and metabolic traits

G. L. Marschmann, J. Tang, K. Zhalnina, U. Karaoz, H. Cho, B. Le, J. Pett-Ridge, E. L. Brodie

The paper predicts life history traits of soil bacteria based on thermodynamic, biophysical, and metabolic traits, showing growth efficiency becomes more important later in plant growth.

bioRxiv · Jun 29, 2022Ecology

Arabidopsis AAR2, a conserved splicing factor in eukaryotes, acts in microRNA biogenesis

L. Fan, B. Gao, Y. Xu, N. Flynn, B. Le, C. You, S. Li, N. Achkar, P. A. Manavellae, X. Chen

This study identifies Arabidopsis AAR2 as a conserved splicing factor that also promotes miRNA biogenesis by interacting with HYL1 and regulating its dephosphorylation.

bioRxiv · Jun 26, 2022Plant Biology

Quantifying Color Vision Changes Associated with Cataracts Using Cone Contrast Thresholds

U. Mehta, A. Diep, K. Nguyen, B. Le, C. Yuh, C. Frambach, J. Doan, A. Wei, A. M. Palma, M. Farid, S. Garg, S. Kedhar, M. Wade, K. A. Marshall, K. A. Jameson, , A. W. Browne

This study quantifies color vision changes in cataract patients and aging individuals using cone contrast thresholds, finding age-related declines in S-cone sensitivity and improvements post-surgery.

bioRxiv · Jun 27, 2020Pathology

Two-Photon Microperimetry: A media opacity-independent retinal function assay

A. Wei, U. V. Mehta, G. Palczewska, A. M. Palma, V. M. Hussey, L. E. Hoffmann, A. Diep, K. Nguyen, B. Le, S. Y.-S. Chang, A. W. Browne

This study evaluates 2-photon infrared microperimetry for assessing retinal function in patients with optical media opacities, finding it provides more consistent results than visible light methods.

bioRxiv · Jun 27, 2020Bioengineering