Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival
J.-P. Leduc-Gaudet, K. Miguez, M. Cefis, A. Moamer, T. J. Chaffer, J. Faitg, O. Reynaud, F. E. Broering, A. Shams, D. Mayaki, L. Huck, M. Sandri, G. Gouspillou, S. Hussain
This study shows that blocking autophagy in skeletal muscles during sepsis worsens muscle dysfunction and reduces survival, suggesting autophagy is protective.
bioRxiv · Aug 5, 2021Cell Biology