Author

M. Cefis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Gouspillou· 3 shared J. A. Morais· 2 shared J.-P. Leduc-Gaudet· 2 shared V. Marcangeli· 2 shared A. Bak· 1 shared A. Moamer· 1 shared A. S. Deshmukh· 1 shared A. Shams· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

G. Gouspillou

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3 papers

Recent·Most cited

The impact of physical activity on physical performance, mitochondrial bioenergetics, ROS production and calcium handling across the human adult lifespan

M. Cefis, V. Marcangeli, R. Hammad, J. Granet, J.-P. Leduc-Gaudet, P. Gaudreau, C. Trumpff, Q. Huang, M. Picard, M. Aubertin-Leheudre, M. Belanger, J. A. Morais, G. Gouspillou

The paper examines how physical activity affects mitochondrial function, ROS production, and calcium handling in skeletal muscle across the human lifespan, finding that aging does not reduce mitochondrial respiration but decreases calcium retention capacity.

bioRxiv · Jul 9, 2024 · PreprintCell Biology

Dysregulated Skeletal Muscle Myosin Super-relaxation and Energetics in Type II Diabetes

C. T. Lewis, R. Moreno-Justicia, L. Savoure, E. Calvo, A. Bak, J. Laitila, R. A. E. Seaborne, S. Larsen, H. Iwamoto, M. Cefis, J. A. Morais, G. Gouspillou, J. Alegre-Cebollada, T. J. Hawke, J. Vazquez, , J. Ochala

This study investigates altered myosin super-relaxation and energy metabolism in type II diabetes using muscle biopsies and proteomic analyses, finding increased super-relaxation and reduced ATP demand.

bioRxiv · Jun 12, 2024 · PreprintCell Biology

Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival

J.-P. Leduc-Gaudet, K. Miguez, M. Cefis, A. Moamer, T. J. Chaffer, J. Faitg, O. Reynaud, F. E. Broering, A. Shams, D. Mayaki, L. Huck, M. Sandri, G. Gouspillou, S. Hussain

This study shows that blocking autophagy in skeletal muscles during sepsis worsens muscle dysfunction and reduces survival, suggesting autophagy is protective.

bioRxiv · Aug 5, 2021Cell Biology