CD99 Promotes Self-renewal in Hematopoietic Stem Cells and Leukemia Stem Cells by Regulating Protein Synthesis
Y. Huang, E. G. Kapti, Y. Ji, T. Thomas, J. Dempsey, K. Mims, I. Berezniuk, L. Guo, B. Kroger, W. Hu, C. Y. Park, S. S. Chung
This study shows CD99 regulates protein synthesis in hematopoietic stem cells and leukemia stem cells, promoting self-renewal and clonal expansion leading to AML.
bioRxiv · Feb 21, 2023Cancer Biology