Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting
R. K. Morgan, K. Wang, L. K. Svoboda, C. A. Rygiel, C. Lalancette, R. Cavalcante, M. S. Bartolomei, R. D. Prasasya, K. Neier, B. P. Perera, T. R. Jones, J. A. Colacino, M. A. Sartor, D. C. Dolinoy
This study examines DNA methylation changes in mouse tissues due to lead and phthalate exposure, identifying tissue- and sex-specific DMRs and their association with genomic imprinting.
bioRxiv · Sep 29, 2023 · PreprintPharmacology & Toxicology